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Cub domain-containing protein

WebMay 21, 2024 · The role of CDCP1 (CUB domain-containing protein 1) and ADAM12 (a disintegrin and metalloproteinase 12) in ovarian cancer. J BUON. 2015;20(3):673–679. 16. Miura S, Hamada S, Masamune A, et al. CUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells. WebJan 7, 2024 · Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3) is a member of a small family of multifunctional cell surface-anchored glycoproteins functioning as co-receptors for a variety of growth factors. ... Ugef, and Bmp1 (CUB)-epidermal growth factor (EGF)-like domain-containing (SCUBE) protein family comprises three related …

(PDF) Targeting CUB Domain-Containing Protein 1 with a …

WebFeb 15, 2024 · CUB domain containing protein 1 (CDCP1), also known as Trask, gp140, SIMA135, and CD318, is a type I single-pass membrane protein that is highly overexpressed in a variety of solid tumors (12 – 14). WebSep 7, 2024 · The mature protein contains 2 putative CUB domains, a consensus type-1 palmitoylation motif, and 5 PxxP motifs that mediate binding to Src (190090) homology-3 domains. Northern blot analysis detected highest expression of a 6.0-kb transcript in skeletal muscle and colon, with lower expression in kidney, small intestine, placenta, and … can i run whatsapp on laptop https://max-cars.net

Structural Requirements for Cub Domain Containing …

WebOct 1, 2024 · CUB domain-containing protein 1 (CDCP1) is a transmembrane glycoprotein that contains three extracellular CUB domains and regulates anchorage … WebMar 2, 2015 · The transmembrane glycoprotein, CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein 1 (CDCP1) is overexpressed in several cancer types and is a predictor of poor prognosis for patients ... WebNational Center for Biotechnology Information five letter words that start with geo

SCUBE3 signal peptide, CUB domain and EGF like domain containing …

Category:Q923L3 - UniProt

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Cub domain-containing protein

CDCP1

WebCUB domain-containing protein 1 (CDCP1) is a substrate of Src family kinases and has been shown to regulate anoikis resistance, migration and matrix degradation during tumor invasion and metastasis in a tyrosine phosphorylation-dependent manner. WebOct 31, 2006 · PTHR24046:SF4 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 1 hit; PROSITE. View protein in PROSITE; PS00010 ASX_HYDROXYL 6 hits; PS01180 CUB 1 hit; PS01186 EGF_2 6 hits; PS50026 EGF_3 6 hits; PS01187 EGF_CA 6 hits; Pfam. View protein in Pfam; PF12662 cEGF 1 hit; …

Cub domain-containing protein

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WebFeb 15, 2024 · Here, we demonstrate that Abs that selectively recognize a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) could enable more effective … WebOct 3, 2024 · Abstract. Rationale: An antibody-drug conjugate (ADC) is a targeted therapy consisting of a cytotoxic payload that is linked to an antibody which targets a protein …

WebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and … WebMar 29, 2024 · CUB domain-containing protein 1 (CDCP1) is a substrate of Src family kinases and has been shown to regulate anoikis resistance, migration and matrix …

WebNing Zhao's 14 research works with 118 citations and 1,017 reads, including: Theranostic Targeting of CUB Domain–Containing Protein 1 (CDCP1) in Multiple Subtypes of Bladder Cancer WebCUB domain-containing protein 1 (CDCP1) is a substrate of Src family kinases and has been shown to regulate anoikis resistance, migration and matrix degradation during …

WebMedChemExpress References: PMID: 37013960 CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) resistance by regulating EGFR signaling pathways and is a potential target in lung Cancer treatment. This study aims to identify a CDCP1 reducer that synergistically …

WebSummary. This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. can i run wifi without an internet providerWebLaw, M. E., Ferreira, R. B., Davis, B. J., Higgins, P. J., Kim, J.-S., Castellano, R. K., … Law, B. K. (2016). CUB domain-containing protein 1 and the epidermal ... five letter words that start with fieWebJun 1, 2008 · One such antigen, CUB domain-containing protein 1 (CDCP1), was recognized by monoclonal antibody 25A11 and is a single transmembrane molecule highly expressed in several metastatic cancers as well ... can i run war thunder on my laptopWebAbstact. To measure the levels of serum CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in patients with ovarian cancer (OvCa), benign gynecological conditions and healthy women and in a number of other cancer … can i run warhammer vermintide 2WebOct 1, 2024 · CUB domain-containing protein 1 (CDCP1) is one of the few transmembrane glycoprotein that contains three extracellular CUB domains and … five letter words that start with hacWebJul 10, 2012 · The deduced 993-amino acid protein has an N-terminal signal sequence, followed by 9 putative calcium-binding EGF-like repeats, a spacer region, and a C-terminal CUB domain. The spacer region contains 5 potential N-glycosylation sites. SCUBE3 was predicted to be secreted as a mature 971-amino acid protein with a calculated molecular … five letter words that start with feWebDec 9, 2010 · CDCP1 Is Up-Regulated in Highly Metastatic Melanoma Cell Lines. CDCP1, also known as SIMA135 or Trask, is a transmembrane glycoprotein that contains three putative extracellular CUB domains. CUB domains are believed to function in protein–protein ( 22, 23) and protein/carbohydrate ( 24) interactions. We initially … five letter words that start with h a i