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Cytotoxicities of co-occurring alternariol

WebThe filamentous fungus Alternaria alternata is a potent producer of many toxic secondary metabolites, which contaminate food and feed. The most prominent one is the polyketide-derived alternariol (AOH) and its derivative alternariol monomethyl ether (AME). Here, we identified the gene cluster for the biosynthesis of AOH and AME by CRISPR/Cas9 ... WebAlternariol and monomethylalternariol are natural phytotoxins produced by some fungal strains, such as Nimbya and Alternaria. These substances confer virulence to phytopathogens, yet no information is available concerning their mode of action. Here we show that in the micromolar range alternariol 9-methyl ether is able to inhibit the …

Frontiers Cytotoxic Effects of Alternariol, Alternariol …

WebMar 1, 2016 · Cytotoxicities of Co-occurring alternariol, alternariol monomethyl ether and tenuazonic acid on human gastric epithelial cells. Huikang Lin, B. Jia, Aibo Wu … WebDetermination of six Alternaria toxins with UPLC-MS/MS and their occurrence in tomatoes and tomato products from the Swiss market Mycotoxin Res. 2011 Nov;27 (4):265-71. doi: 10.1007/s12550-011-0103-x. Epub 2011 Jun 22. Authors Jürg Noser 1 , Patrick Schneider , Martin Rother , Hansruedi Schmutz Affiliation trugreen fort collins https://max-cars.net

Determination of six Alternaria toxins with UPLC-MS/MS and their ...

WebJan 1, 2024 · Article on Cytotoxicities of Co-occurring alternariol, alternariol monomethyl ether and tenuazonic acid on human gastric epithelial cells, published in Food and Chemical Toxicology 171 on 2024-01-01 by Bingxuan Jia+2. WebFeb 1, 2024 · Humans are typically exposed to mixtures of substances, whereby their bioactivity can be significantly altered by co-occurring compounds. Thus, over the last years, research on combinatory effects has gained increasing attention. ... Combinatory estrogenic effects of bisphenol A in mixtures with alternariol and zearalenone in human … WebThe co-occurrence of DON with emerging Alternaria toxins was reported in previous studies [37,38]. Babič et al. (2024) [37] reported that DON and TeA were present in 32% and 26% of cereal grain... trugreen fort wayne

Role of quercetin on Caco-2 cells against cytotoxic effects of ...

Category:Occurrence of alternariol and alternariol monomethyl ether …

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Cytotoxicities of co-occurring alternariol

Determination of six Alternaria toxins with UPLC-MS/MS and their ...

WebAbstract. The mycotoxin alternariol (AOH) is produced by Alternaria fungi. It occurs naturally in foodstuffs and is frequently found as contaminant in fruit and grain products. Most information regarding AOH toxicity and the potential mechanisms involved comes from in vitro studies, as only very limited in vivo studies have been performed. WebApr 22, 2024 · The co-occurrence of Alternaria mycotoxins has recently been reviewed ( Crudo et al., 2024 ). Most of the investigated food commodities are found to be …

Cytotoxicities of co-occurring alternariol

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WebMar 1, 2016 · Alternaria toxins such as alternariol (AOH) and its naturally occurring monomethyl ether (AME) produce cytotoxicity and oxidative stress in cell cultures. On the other hand, it has been proved that natural polyphenols have antioxidant effect. Quercetin (Quer) is a polyphenol present in berries and other commodities which exhibits these … WebAug 1, 2012 · Alternariol, AME and TA were the most studied Alternaria toxins. The mean levels of AME ranged from 0.13 mg/kg (maize) to 320 mg/kg (soy beans) [53, 61], AOH levels from 0.16 mg/kg (maize) to...

Web7 rows · Jan 1, 2024 · Alternariol (AOH), alternariol monomethyl ether (AME) and tenuazonic acid (TeA) are the three ... WebJan 14, 2015 · Abstract. A total of 70 tomato-based and 86 citrus-based products collected in China were analyzed for alternariol, alternariol monomethyl ether, tentoxin, and tenuazonic acid by ultraperformance liquid chromatography–electrospray ionization–tandem mass spectrometry. No toxins were found in any fresh tomato or citrus fruit samples.

WebJan 1, 2024 · Alternaria toxins widely contaminate vegetables, fruits, cereals, and oil crops, especially three toxins, AOH, AME, and TeA; their levels of contamination are closely … WebMar 24, 2024 · The highest levels of alternariol and alternariol methyl ether were found in lentils, oilseeds, tomatoes, carrots, juices, wines, and cereals. Tenuazonic acid highest levels were detected in cereals followed by beer, while alternariol, alternariol methyl ether, tenuazonic acid, and tentoxin were found in legumes, nuts, and oilseeds. 1.

WebAlternariol (AOH), alternariol monomethyl-ether (AME), and tenuazonic acid (TeA) are major mycotoxins produced by fungi of the genus Alternaria and are common …

WebAug 1, 2012 · A. alternata produces a number of mycotoxins, including alternariol, alternariol monomethyl ether, altenuene, altertoxins I, II, III, tenuazonic acid and other … philip meyer attorneyWebDeoxynivalenol (DON) and emerging Alternaria toxins often co-occur in cereal-based products, but the current risk assessment is commonly conducted for only one type of mycotoxin at a time. Compared to adults, infants and young children are more susceptible to mycotoxins through food consumption, especially with cereal-based food products which … philip meyer attorney chattanoogaWebThe mycotoxin alternariol (AOH) is produced by Alternaria fungi. It occurs naturally in foodstuffs and is frequently found as contaminant in fruit and grain products. Most … philip mexesWebApr 22, 2024 · The co-occurrence of Alternaria mycotoxins has recently been reviewed ( Crudo et al., 2024 ). Most of the investigated food commodities are found to be simultaneously contaminated with both AOH and AME in approximately the same concentrations ranges (1:1 ratio). trugreen fort wayne indianaWebNov 25, 2024 · Cytotoxicities of Co-occurring alternariol, alternariol monomethyl ether and tenuazonic acid on human gastric epithelial cells. 1 Europe PMC requires … trugreen franchiseWebJun 1, 2001 · In this study, the possible toxic effects of Alternariol Methyl Ether (AME) and Tenuazonic Acid (TeA) produced by Alternaria species on esophagus of mice were … trugreen fort worthWebSep 14, 2024 · A new isocoumarin compound named setosphacohol A ( 1 ), together with six known ones, alternariol ( 2 ), isoaltenuene ( 3 ), phomasatin ( 4 ), alternariol 5-O-methyl ether ( 5 ), 1-deoxyrubralactone ( 6 ), and rubralactone ( 7 ), was isolated from the entomogenous fungus Setosphaeria sp. philip meyer-horn